Three New 3,6-Dioxygenated Diketopiperazines from the Basidiomycete Lepista sordida

被引：21

作者：

Chen, Xiang-Lian ^{[1
,2
,3
]}

Wu, Min ^{[1
]}

Ti, Hui-Hui ^{[1
]}

Wei, Xiao-Yi ^{[1
]}

Li, Tai-Hui ^{[2
]}

机构：

[1] Chinese Acad Sci, S China Bot Garden, Key Lab Plant Resources Conservat & Sustainable U, Guangzhou 510650, Guangdong, Peoples R China

[2] Guangdong Inst Microbiol, Guangdong Key Lab Microbial Culture Collect & App, Guangdong Prov Publ Lab New Microbial Applicat Te, Guangzhou 510070, Guangdong, Peoples R China

[3] Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China

来源：

HELVETICA CHIMICA ACTA | 2011年 / 94卷 / 08期

基金：

中国国家自然科学基金;

关键词：

DIOXOPIPERAZINE METABOLITES; FUNGUS; CHEMISTRY;

D O I：

10.1002/hlca.201000455

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

Three new 3,6-dioxygenated diketopiperazines, lepistamides A-C (1 - 3), along with a known compound, diatretol (4), were isolated from the mycelial solid cultures of the basidiomycete Lepista sordida. Their structures were elucidated by spectroscopic means. The isolated diketopiperazines were evaluated for the cytotoxic activity against Astc-a-1, Bel 7402, and HeLa cell lines, and their biogenetic pathway was discussed.

引用

页码：1426 / 1430

页数：5

共 18 条

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[2]

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