Biodegradable thermoreversible gelling PLGA-g-PEG copolymers

被引：83

作者：

Jeong, B ^{[1
]}

Wang, LQ ^{[1
]}

Gutowska, A ^{[1
]}

机构：

[1] Pacific NW Natl Lab, Richland, WA 99352 USA

来源：

CHEMICAL COMMUNICATIONS | 2001年 / 16期

关键词：

D O I：

10.1039/b102819g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The thermogelling aqueous Solution Of poly(DL-lactic acid-co-glycolic acid) grafted with poly(ethylene glycol)s is developed, and the elegant instrumental methods to determine sol-gel transition temperature and the method to control get duration are reported.

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页码：1516 / 1517

页数：2

相关论文

共 16 条

[1] MICELLIZATION OF POLY(ETHYLENE OXIDE)-POLY(PROPYLENE OXIDE)-POLY(ETHYLENE OXIDE) TRIBLOCK COPOLYMERS IN AQUEOUS-SOLUTIONS - THERMODYNAMICS OF COPOLYMER ASSOCIATION [J].

ALEXANDRIDIS, P ;

HOLZWARTH, JF ;

HATTON, TA .

MACROMOLECULES, 1994, 27 (09) :2414-2425

[2] Site-specific polymer-streptavidin bioconjugate for pH-controlled binding and triggered release of biotin [J].

Bulmus, V ;

Ding, ZL ;

Long, CJ ;

Stayton, PS ;

Hoffman, AS .

BIOCONJUGATE CHEMISTRY, 2000, 11 (01) :78-83

[3]

Cho KY, 1999, MACROMOL RAPID COMM, V20, P598, DOI 10.1002/(SICI)1521-3927(19991101)20:11<598::AID-MARC598>3.0.CO

[4]

2-1

[5] Thermoreversible gelation of PEG-PLGA-PEG triblock copolymer aqueous solutions [J].

Jeong, B ;

Bae, YH ;

Kim, SW .

MACROMOLECULES, 1999, 32 (21) :7064-7069

[6] Biodegradable thermosensitive micelles of PEG-PLGA-PEG triblock copolymers [J].

Jeong, B ;

Bae, YH ;

Kim, SW .

COLLOIDS AND SURFACES B-BIOINTERFACES, 1999, 16 (1-4) :185-193

[7] Drug release from biodegradable injectable thermosensitive hydrogel of PEG-PLGA-PEG triblock copolymers [J].

Jeong, B ;

Bae, YH ;

Kim, SW .

JOURNAL OF CONTROLLED RELEASE, 2000, 63 (1-2) :155-163

[8] Thermogelling biodegradable polymers with hydrophilic backbones:: PEG-g-PLGA [J].

Jeong, B ;

Kibbey, MR ;

Birnbaum, JC ;

Won, YY ;

Gutowska, A .

MACROMOLECULES, 2000, 33 (22) :8317-8322

[9]

JEONG B, 2001, UNPUB

[10] SELF-ASSEMBLY IN AQUEOUS BLOCK COPOLYMER SOLUTIONS [J].

MALMSTEN, M ;

LINDMAN, B .

MACROMOLECULES, 1992, 25 (20) :5440-5445