Phagocytes may engulf both apoptotic and viable cells via calreticulin on the surface of the target cell, through its interaction with the phagocyte receptor, LRP. In reality, however, only apoptotic cells are engulfed, apparently because their surface ligand CD47 is prevented from activating the inhibitory phagocyte receptor SIRP alpha.
机构:
Natl Jewish Med & Res Ctr, Dept Pediat, Cell Biol Program, Denver, CO 80206 USANatl Jewish Med & Res Ctr, Dept Pediat, Cell Biol Program, Denver, CO 80206 USA
Fadok, VA
Bratton, DL
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Natl Jewish Med & Res Ctr, Dept Pediat, Cell Biol Program, Denver, CO 80206 USANatl Jewish Med & Res Ctr, Dept Pediat, Cell Biol Program, Denver, CO 80206 USA
Bratton, DL
Guthrie, L
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Natl Jewish Med & Res Ctr, Dept Pediat, Cell Biol Program, Denver, CO 80206 USANatl Jewish Med & Res Ctr, Dept Pediat, Cell Biol Program, Denver, CO 80206 USA
Guthrie, L
Henson, PM
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机构:
Natl Jewish Med & Res Ctr, Dept Pediat, Cell Biol Program, Denver, CO 80206 USANatl Jewish Med & Res Ctr, Dept Pediat, Cell Biol Program, Denver, CO 80206 USA
机构:
Natl Jewish Med & Res Ctr, Dept Pediat, Cell Biol Program, Denver, CO 80206 USANatl Jewish Med & Res Ctr, Dept Pediat, Cell Biol Program, Denver, CO 80206 USA
Fadok, VA
Bratton, DL
论文数: 0引用数: 0
h-index: 0
机构:
Natl Jewish Med & Res Ctr, Dept Pediat, Cell Biol Program, Denver, CO 80206 USANatl Jewish Med & Res Ctr, Dept Pediat, Cell Biol Program, Denver, CO 80206 USA
Bratton, DL
Guthrie, L
论文数: 0引用数: 0
h-index: 0
机构:
Natl Jewish Med & Res Ctr, Dept Pediat, Cell Biol Program, Denver, CO 80206 USANatl Jewish Med & Res Ctr, Dept Pediat, Cell Biol Program, Denver, CO 80206 USA
Guthrie, L
Henson, PM
论文数: 0引用数: 0
h-index: 0
机构:
Natl Jewish Med & Res Ctr, Dept Pediat, Cell Biol Program, Denver, CO 80206 USANatl Jewish Med & Res Ctr, Dept Pediat, Cell Biol Program, Denver, CO 80206 USA