Correction of bone marrow failure in dyskeratosis congenita by bone marrow transplantation

被引：28

作者：

Ghavamzadeh, A ^{[1
]}

Alimoghadam, K ^{[1
]}

Nasseri, P ^{[1
]}

Jahani, M ^{[1
]}

Khodabandeh, A ^{[1
]}

Ghahremani, G ^{[1
]}

机构：

[1] Univ Tehran Med Sci, Shariati Hosp, Dept Oncol, Hematol & Bone Marrow Transplantat Unit, Tehran 14114, Iran

来源：

BONE MARROW TRANSPLANTATION | 1999年 / 23卷 / 03期

关键词：

allogeneic bone marrow transplantation; constitutional anemia; dyskeratosis congenita;

D O I：

10.1038/sj.bmt.1701567

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

Dyskeratosis congenita is recognized by its dermal lesions and constitutional aplastic anemia in some cases. We report successful allogeneic bone marrow transplantation in two siblings with this disease from their sister, and their long term follow-up. We used reduced doses of cyclophosphamide and busulfan for conditioning instead of total body irradiation. Also, we report late adverse effects of transplantation which are not distinguishable from the natural course of disease.

引用

页码：299 / 301

页数：3

共 13 条

[1] LATE VASCULAR COMPLICATIONS AFTER BONE-MARROW TRANSPLANTATION FOR DYSKERATOSIS-CONGENITA [J].