Structural basis of Hox specificity

被引：24

作者：

Wilson, DS ^{[1
]}

Desplan, C

机构：

[1] Massachusetts Gen Hosp, Boston, MA 02114 USA

[2] Rockefeller Univ, New York, NY 10021 USA

来源：

NATURE STRUCTURAL BIOLOGY | 1999年 / 6卷 / 04期

关键词：

D O I：

10.1038/7524

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

On their own, the homeotic selector (Hox) transcriptional regulators bind very short, rather similar DNA sequences. To elevate their functional specificity, Hox proteins heterodimerize with other homeodomain-containing proteins. The structural basis for this fruitful partnership is now coming into view.

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页码：297 / 300

页数：4

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