Copper catalyzed azide-alkyne cycloadditions on solid surfaces: Applications and future directions

被引：95

作者：

Devaraj, Neal K. ^{[1
]}

Collman, James P. ^{[1
]}

机构：

[1] Stanford Univ, Dept Chem, Stanford, CA 94305 USA

来源：

QSAR & COMBINATORIAL SCIENCE | 2007年 / 26卷 / 11-12期

关键词：

bioconjugation; click-chemistry; catalysis; surfaces; triazole;

D O I：

10.1002/qsar.200740121

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The Copper Catalyzed Azide-Alkyne Cycloaddition (CuAAC), a paradigm of "click" chemistry has found numerous applications in the field of surface chemistry. This minireview discusses the reaction from a surface chemist's perspective. Specific advantages, limitations, and surface related concerns are discussed. We review the types of solid surfaces that have been modified via click chemistry and conclude with several elegant applications.

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页码：1253 / 1260

页数：8

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