The pathogenesis of psoriasis and the mechanism of action of tazarotene

被引：38

作者：

Duvic, M

Asano, AT

Hager, C

Mays, S

机构：

[1] Univ Texas, MD Anderson Cancer Ctr, Dermatol Sect, Houston, TX 77030 USA

[2] Univ Texas, Sch Med, Dept Dermatol, Houston, TX 77030 USA

来源：

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY | 1998年 / 39卷 / 04期

关键词：

D O I：

10.1016/S0190-9622(98)70309-3

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

The 3 major features of psoriasis-abnormal differentiation of keratinocytes, hyperproliferation of keratinocytes, and infiltration of inflammatory components into the skin-can be quantified by measuring levels of certain biochemical markers. Psoriasis is associated with upregulation or downregulation of several of these markers. Tazarotene helps to normalize the levels of the markers, thereby bringing about clinical improvement.

引用

页码：S129 / S133

页数：5

共 28 条

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