Conservative treatment may be beneficial for young women with atypical endometrial hyperplasia or endometrial adenocarcinoma

Objective: To evaluate whether an alternative treatment to radical hysterectomy exists for young women with endometrial adenocarcinoma. Design: A review of the literature (70 articles) plus personal results. Setting: University hospital. Patient(s): Women with atypical endometrial hyperplasia or adenocarcinoma. Main Outcome Measure(s): The recurrence rate and the pregnancy rate after conservative therapy. Conclusion(s): Conservative treatment of well-differentiated stage I endometrial adenocarcinoma can be considered in young patients, with close surveillance to diagnose any possible recurrence. (C) 2003 by American Society for Reproductive Medicine.