A new perspective on nonprescription statins: An opportunity for patient education and involvement

被引:8
作者
Fuster, Valentin [1 ]
机构
[1] CUNY Mt Sinai Sch Med, Marie Josee & Henry R Kravis Ctr Cardiovasc Hlth, Zena & Michael A Wiener Cardiovasc Inst, New York, NY 10029 USA
关键词
D O I
10.1016/j.amjcard.2007.06.009
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Education of the public and encouragement of patients' involvement in their own health care have been repeatedly proved effective means of increasing health awareness, promoting lifestyle modifications, and improving early disease detection in a variety of clinical scenarios. Despite substantial efforts from different public and private organizations to educate the population on cardiovascular risk, coronary heart disease remains the leading cause of death in the United States, and its prevalence continues to grow. Therefore, alternative approaches with the potential to elicit a meaningful impact in the community deserve consideration. A nonprescription statin program could provide consumers with a tool of proved benefit in cardiovascular risk prevention. The magnitude of the target population (millions of subjects with intermediate to high risk), as well as the safety and efficacy profile of lovastatin 20 mg, support the consideration of this drug for "over-thecounter" availability. Moreover, a nonprescription statin program could represent a unique opportunity not only to enhance patients' involvement in primary prevention but also to reinforce the education of the public and to encourage interaction with health care providers. The success of such a program will undoubtedly require precise labeling of the risks and benefits of the therapy, as well as active support and participation from major medical organizations. In conclusion, nonprescription statin availability, through enhanced unique patients' involvement, offers the potential for enormous public health benefit. (c) 2007 Elsevier Inc. All rights reserved. (Am J Cardiol 2007;100:907-910)
引用
收藏
页码:907 / 910
页数:4
相关论文
共 25 条
[1]   The argument against the appropriateness of over-the-counter statins [J].
Barter, Philip J. ;
Rye, Kerry-Anne .
CIRCULATION, 2006, 114 (12) :1315-1320
[2]   Long-term persistence in use of statin therapy in elderly patients [J].
Benner, JS ;
Glynn, RJ ;
Mogun, H ;
Neumann, PJ ;
Weinstein, MC ;
Avorn, J .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2002, 288 (04) :455-461
[3]   Potential impact on cardiovascular public health of over-the-counter statin availability [J].
Brass, EP ;
Allen, SE ;
Melin, JM .
AMERICAN JOURNAL OF CARDIOLOGY, 2006, 97 (06) :851-856
[4]  
Choudhry NK, 2005, ANN INTERN MED, V142, P910, DOI 10.7326/0003-4819-142-11-200506070-00009
[5]   Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III) [J].
Cleeman, JI ;
Grundy, SM ;
Becker, D ;
Clark, LT ;
Cooper, RS ;
Denke, MA ;
Howard, WJ ;
Hunninghake, DB ;
Illingworth, DR ;
Luepker, RV ;
McBride, P ;
McKenney, JM ;
Pasternak, RC ;
Stone, NJ ;
Van Horn, L ;
Brewer, HB ;
Ernst, ND ;
Gordon, D ;
Levy, D ;
Rifkind, B ;
Rossouw, JE ;
Savage, P ;
Haffner, SM ;
Orloff, DG ;
Proschan, MA ;
Schwartz, JS ;
Sempos, CT ;
Shero, ST ;
Murray, EZ .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2001, 285 (19) :2486-2497
[6]   Primary prevention with over-the-counter statins: A cautionary tale [J].
Davidoff, F .
CLINICAL PHARMACOLOGY & THERAPEUTICS, 2005, 78 (03) :218-220
[7]   Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS): Additional perspectives on tolerability of long-term treatment with lovastatin [J].
Downs, JR ;
Clearfield, M ;
Tyroler, HA ;
Whitney, EJ ;
Kruyer, W ;
Langendorfer, A ;
Zagrebelsky, V ;
Weis, S ;
Shapiro, DR ;
Beere, PA ;
Gotto, AM .
AMERICAN JOURNAL OF CARDIOLOGY, 2001, 87 (09) :1074-1079
[8]   Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels - Results of AFCAPS/TexCAPS [J].
Downs, JR ;
Clearfield, M ;
Weis, S ;
Whitney, E ;
Shapiro, DR ;
Beere, PA ;
Langendorfer, A ;
Stein, EA ;
Kruyer, W ;
Gotto, AM .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1998, 279 (20) :1615-1622
[9]   Demographics and cardiology, 1950-2050 [J].
Foot, DK ;
Lewis, RP ;
Pearson, TA ;
Beller, GA .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2000, 35 (05) :66B-80B
[10]   The distribution of 10-year risk for coronary heart disease among US adults - Findings from the National Health and Nutrition Examination Survey III [J].
Ford, ES ;
Giles, WH ;
Mokdad, AH .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2004, 43 (10) :1791-1796