Comparative in vitro activities of investigational peptide deformylase inhibitor NVP LBM-415 and other agents against human mycoplasmas and ureaplasmas

被引：15

作者：

Waites, KB ^{[1
]}

Reddy, NB ^{[1
]}

Crabb, DA ^{[1
]}

Duffy, LB ^{[1
]}

机构：

[1] Univ Alabama, Dept Pathol, Birmingham, AL 35249 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2005年 / 49卷 / 06期

关键词：

D O I：

10.1128/AAC.49.6.2541-2542.2005

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Peptide deformylase inhibitor LBM-415 and seven other drugs were tested against Mycoplasma pneumoniae (100 isolates), Mycoplasma hominis (20 isolates), Mycoplasma fermentans (10 isolates), and Ureaplasma species (50 isolates). LBM-415 was active against M. pneumoniae (MICs, ≤ 0.008 μ kg/ml). It showed no activity against M. hominis and M. fermentans and modest activity against Ureaplasma spp.

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页码：2541 / 2542

页数：2

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