Antioxidant, antibacterial, and antiviral effects of Lactuca sativa extracts

被引：28

作者：

Edziri, H. L. ^{[1
]}

Smach, M. A. ^{[4
]}

Ammar, S. ^{[3
]}

Mahjoub, M. A. ^{[3
]}

Mighri, Z. ^{[3
]}

Aouni, M. ^{[1
]}

Mastouri, M. ^{[2
]}

机构：

[1] Fac Pharm, Lab Malad Transmissibles & Subst Biol Act, Monastir 5000, Australia

[2] Lab Microbiol CHU Fattouma Bouguiba, Monastir 5000, Australia

[3] Fac Sci Monastir, Lab Chim Subst Nat & Synth Orga 99 UR 12 26, Monastir 5000, Australia

[4] Fac Med, Biochim Lab, Sousse 4000, Tunisia

来源：

INDUSTRIAL CROPS AND PRODUCTS | 2011年 / 34卷 / 01期

关键词：

Lactuca sativa var longifolia; Antioxidant; Antibacterial; Antiviral; Activity; L; ANTIFUNGAL;

D O I：

10.1016/j.indcrop.2011.04.003

中图分类号：

S2 [农业工程];

学科分类号：

0828 ;

摘要：

Antioxidant, antibacterial and antiviral effects of aqueous and methanol extracts of Lactuca sativa var longifolia leaves were investigated. The antioxidant activity was evaluated using the DPPH assay. The effect of the extracts against 5 Gram-positive and 6 Gram-negative bacteria was tested. The antiviral activity was determined against human cytomegalovirus (HCMV) strain AD-169 (ATCC Ref. VR 538) and coxsackie B virus type 3 (CoxB-3) using a cytopathic effect (CPE) reduction assay. The methanol extract had the highest total phenolic contents (235.31 mg CE/g extract). It exhibited a significantly (p < 0.05) greater hydroxyl radical-scavenging activity (IC50 = 3.5 mu g/ml) than the aqueous extract (4.1 mu g/ml). It was also the most effective extract with the lowest MIC (2.5 mg/ml) against all Gram negative and Gram positive bacteria. Methanol and aqueous extracts exhibited antiviral activity against HCMV and Cox-B3 viruses with IC50 of 200 mu/ml. (C) 2011 Elsevier B.V. All rights reserved.

引用

页码：1182 / 1185

页数：4

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