Application of distance geometry to 3D visualization of sequence relationships

被引:8
作者
Forster, MJ [1 ]
Heath, AB [1 ]
Afzal, MA [1 ]
机构
[1] Natl Inst Biol Stand & Controls, S Mimms EN6 3QG, Herts, England
关键词
D O I
10.1093/bioinformatics/15.1.89
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
We describe the application of distance geometry methods to the three-dimensional visualization of sequence relationships, with examples for mumps virus SH gene cDNA and prion protein sequences. Sequence-sequence distance measures may be obtained from either a multiple sequence alignment or from sets of pairwise alignments.
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页码:89 / 90
页数:2
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