Did the four human cancer cell lines DLD-1, HCT-15, HCT-8, and HRT-18 originate from one and the same patient?

被引：43

作者：

Vermeulen, SJ

Chen, TR

Speleman, F

Nollet, F

Van Roy, FM

Mareel, MM

机构：

[1] State Univ Ghent Hosp, Dept Radiotherapy & Nucl Med, Expt Cancerol Lab, B-9000 Ghent, Belgium

[2] Amer Type Culture Collect, Rockville, MD USA

[3] State Univ Ghent Hosp, Dept Med Genet, B-9000 Ghent, Belgium

[4] VIB, Mol Cell Biol Lab, Ghent, Belgium

[5] State Univ Ghent, B-9000 Ghent, Belgium

来源：

CANCER GENETICS AND CYTOGENETICS | 1998年 / 107卷 / 01期

关键词：

D O I：

10.1016/S0165-4608(98)00081-8

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Four human colon cancer cell lines, HCT-8, HRT-18, DLD-1, and HCT-15, with an epithelioid morphotype reproducibly formed alpha-catenin-deficient round cells. Using DNA fingerprinting, we found that these four cell lines have an identical genetic background. Our finding strongly suggests a genetic background for the reproducible loss of alpha-catenin and the ensuing acquisition of invasiveness in all four cell lines. (C) Elsevier Science Inc., 1998.

引用

页码：76 / 79

页数：4

共 18 条

[1] TISSUE TYPING THE HLA-A LOCUS FROM GENOMIC DNA BY SEQUENCE-SPECIFIC PCR - COMPARISON OF HLA GENOTYPE AND SURFACE EXPRESSION ON COLORECTAL TUMOR-CELL LINES
BROWNING, MJ
KRAUSA, P
ROWAN, A
BICKNELL, DC
BODMER, JG
BODMER, WF
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (07) : 2842 - 2845
[2] EXPRESSION OF THE INTERFERON-GAMMA RECEPTOR GENE IN MOUSE PLACENTAS IS RELATED TO STAGE OF GESTATION AND IS RESTRICTED TO SPECIFIC SUBPOPULATIONS OF TROPHOBLAST CELLS
CHEN, HL
KAMATH, R
PACE, JL
RUSSELL, SW
HUNT, JS
[J]. PLACENTA, 1994, 15 (02) : 109 - 121
[3] PURIFICATION AND PROPERTIES OF A P-NITROBENZYL ESTERASE FROM BACILLUS-SUBTILIS
CHEN, YR
USUI, S
QUEENER, SW
YU, CA
[J]. JOURNAL OF INDUSTRIAL MICROBIOLOGY, 1995, 15 (01): : 10 - 18
[4] POLYMERASE-DELTA VARIANTS IN RER COLORECTAL TUMORS
DACOSTA, LT
LIU, B
ELDEIRY, WS
HAMILTON, SR
KINZLER, KW
VOGELSTEIN, B
MARKOWITZ, S
WILLSON, JKV
DELACHAPELLE, A
DOWNEY, KM
SO, AG
[J]. NATURE GENETICS, 1995, 9 (01) : 10 - 11
[5] DEXTER DL, 1979, CANCER RES, V39, P1020
[6] Progression of familial adenomatous polyposis (FAP) colonic cells after transfer of the src or polyoma middle T oncogenes: Cooperation between src and HGF/Met in invasion
Empereur, S
Djelloul, S
DiGioia, Y
Bruyneel, E
Mareel, M
VanHengel, J
VanRoy, F
Comoglio, P
Courtneidge, S
Paraskeva, C
Chastre, E
Gespach, C
[J]. BRITISH JOURNAL OF CANCER, 1997, 75 (02) : 241 - 250
[7] HATT H, 1992, ATCC Q NEWSLETT, V12, P2
[8] KING BL, 1994, AM J PATHOL, V144, P486
[9] DNA-FINGERPRINTING DISPUTE LAID TO REST
LANDER, ES
BUDOWLE, B
[J]. NATURE, 1994, 371 (6500) : 735 - 738
[10] LEIBOVITZ A, 1976, CANCER RES, V36, P4562

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