In search of tuberculosis virulence genes

被引：25

作者：

Collins, DM

机构：

[1] AgResearch, Wallaceville Animal Research Centre, Upper Hutt

来源：

TRENDS IN MICROBIOLOGY | 1996年 / 4卷 / 11期

关键词：

D O I：

10.1016/0966-842X(96)10066-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The identity of the virulence genes that enable tuberculosis organisms to survive in macrophages and to induce the features of tuberculosis remains largely unknown. Numerous putative virulence genes have been identified, but so far there is only conclusive evidence for the role of two genes, katG and rpoV, in virulence.

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页码：426 / 430

页数：5

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