Optic neuropathy in primary antiphospholipid syndrome in childhood

被引：11

作者：

Besbas, N ^{[1
]}

Anlar, B ^{[1
]}

Apak, A ^{[1
]}

Kansu, T ^{[1
]}

机构：

[1] Hacettepe Univ, Dept Neurol, Ankara, Turkey

来源：

JOURNAL OF CHILD NEUROLOGY | 2001年 / 16卷 / 09期

关键词：

D O I：

10.1177/088307380101600914

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Neurologic symptoms associated with antiphospholipid antibodies in children include thrombotic events, unilateral movement disorders, or migraine. We present a 7-year-old girl with bilateral optic neuropathy, cerebral white-matter lesions, and antiphospholipid IgM that responded to prednisone mid tended to relapse when it was stopped. Remission was obtained under maintenance corticosteroid therapy, and the antiphospholipid antibodies disappeared. This case suggests a role for antiphospholipid antibodies in the pathogenesis of optic neuropathy in childhood.

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页码：690 / 693

页数：4

相关论文

共 14 条

[1] Neurological disorders, other than stroke, associated with antiphospholipid antibodies in childhood [J].

Angelini, L ;

Zibordi, F ;

Zorzi, G ;

Nardocci, N ;

Caporali, R ;

Ravelli, A ;

Martini, A .

NEUROPEDIATRICS, 1996, 27 (03) :149-153

[2] HEMIDYSTONIA SYMPTOMATIC OF PRIMARY ANTIPHOSPHOLIPID SYNDROME IN CHILDHOOD [J].

ANGELINI, L ;

RUMI, V ;

NARDOCCI, N ;

COMBI, ML ;

BRUZZONE, MG ;

PELLEGRINI, G .

MOVEMENT DISORDERS, 1993, 8 (03) :383-386

[3]

BESBAS N, 1994, EUR J PEDIATR, V153, P891, DOI 10.1007/BF01954739

[4] Anticardiolipin antibodies in childhood rheumatic disorders [J].

Gedalia, A ;

Molina, JF ;

García, CO ;

Doggett, S ;

Espinoza, LR ;

Gharavi, AE .

LUPUS, 1998, 7 (08) :551-553

[5] Optic neuropathy in systemic lupus erythematosus and antiphospholipid syndrome (APS): Clinical features, pathogenesis, review of the literature and proposed ophthalmological criteria for APS diagnosis [J].

Giorgi, D ;

Gabrieli, CB .

CLINICAL RHEUMATOLOGY, 1999, 18 (02) :124-131

[6] A subgroup of multiple sclerosis patients with anticardiolipin antibodies and unusual clinical manifestations: Do they represent a new nosological entity? [J].

Karussis, D ;

Leker, RR ;

Ashkenazi, A ;

Abramsky, O .

ANNALS OF NEUROLOGY, 1998, 44 (04) :629-634

[7] Chorea as the presenting clinical feature of primary antiphospholipid syndrome in childhood [J].

Kiechl-Kohlendorfer, U ;

Ellemunter, H ;

Kiechl, S .

NEUROPEDIATRICS, 1999, 30 (02) :96-98

[8]

MOLAD Y, 1992, J RHEUMATOL, V19, P556

[9] CHILDHOOD STROKE AND LUPUS ANTICOAGULANT [J].

OLSON, JC ;

KONKOL, RJ ;

GILL, JC ;

DOBYNS, WB ;

COULL, BM .

PEDIATRIC NEUROLOGY, 1994, 10 (01) :54-57

[10] Antiphospholipid antibody syndrome in pediatric patients [J].

Ravelli, A ;

Martini, A .

RHEUMATIC DISEASE CLINICS OF NORTH AMERICA, 1997, 23 (03) :657-+