Polyelectrolyte films boost progenitor cell differentiation into endothelium-like monolayers

被引：30

作者：

Berthelemy, Nicolas ^{[1
]}

Kerdjoudj, Halima ^{[1
]}

Gaucher, Caroline ^{[1
]}

Schaaf, Pierre ^{[2
]}

Stolz, Jean-Francois ^{[1
]}

Lacolley, Patrick ^{[3
]}

Voegel, Jean-Claude ^{[4
]}

Menu, Patrick ^{[1
]}

机构：

[1] UHP Nancy 1, Fac Med, LEMTA UMR CNRS 7563, Bioengn Grp, F-54505 Vandoeuvre Les Nancy, France

[2] Inst Charles Sadron, UPR 22, CNRS, F-67083 Strasbourg, France

[3] UHP Nancy 1, Fac Med, Inst Natl Sante & Rech Med, INSERM,U684, F-54505 Vandoeuvre Les Nancy, France

[4] ULP Strasbourg, Fac Chirug Dentaire, INSERM, Inst Natl Sante & Rech Med,U595, F-67085 Strasbourg, France

来源：

ADVANCED MATERIALS | 2008年 / 20卷 / 14期

关键词：

D O I：

10.1002/adma.200702418

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Rapid differentiation of endothelial progenitor cells (EPCs) into confluent mature endothelial cells (see figure) is important in tissue engineering for the design of autologous, nonthrombotic, vascular grafts. A new method based on EPC culture on poly(sodium-4styrene-sulfonate)/poly(allylamine hydrochloride), that is, polyelectrolyte-multilayer-coated substrates, reduces the time from two months to two weeks.

引用

页码：2674 / +

页数：6

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