Ratiometric photoacoustic sensing of pH using a "sonophore"

被引：23

作者：

Horvath, Thomas D. ^{[1
]}

Kim, Gwangseong ^{[1
]}

Kopelman, Raoul ^{[1
]}

Ashkenazi, Shai ^{[2
]}

机构：

[1] Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA

[2] Univ Michigan, Dept Biomed Engn, Ann Arbor, MI 48109 USA

来源：

ANALYST | 2008年 / 133卷 / 06期

关键词：

D O I：

10.1039/b800116b

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

This work describes ratiometric photoacoustic chemical sensing of pH, and describes how these measurements can be applied as a ratiometric biomedical imaging modality to image pH in intact biological tissue.

引用

页码：747 / 749

页数：3

共 12 条

[1]

ABELHELM K, 1998, FRESEN J ANAL CHEM, V338, P259

[2]

BELL AG, 1881, PHILOS MAG, V11, P156

[3] Optochemical nanosensor PEBBLEs: photonic explorers for bioanalysis with biologically localized embedding [J].

Buck, SM ;

Koo, YEL ;

Park, E ;

Xu, H ;

Philbert, MA ;

Brasuel, MA ;

Kopelman, R .

CURRENT OPINION IN CHEMICAL BIOLOGY, 2004, 8 (05) :540-546

[4] CALCIUM-BINDING TO FLUORESCENT CALCIUM INDICATORS - CALCIUM GREEN, CALCIUM ORANGE AND CALCIUM CRIMSON [J].

EBERHARD, M ;

ERNE, P .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1991, 180 (01) :209-215

[5]

Koo YEL, 2007, ACS SYM SER, V963, P200

[6] Deeply penetrating photoacoustic tomography in biological tissues enhanced with an optical contrast agent [J].

Ku, G ;

Wang, LHV .

OPTICS LETTERS, 2005, 30 (05) :507-509

[7]

Lakowicz J. R., 1999, PRINCIPLES FLUORESCE

[8] Synthesis and photophysical properties of new fluorinated benzo[c]xanthene dyes as intracellular pH indicators [J].

Liu, JX ;

Diwu, ZJ ;

Leung, WY .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2001, 11 (22) :2903-2905

[9] Initial results of in vivo non-invasive cancer imaging in the human breast using near-infrared photoacoustics [J].

Manohar, Srirang ;

Vaartjes, Susanne E. ;

van Hespen, Johan C. G. ;

Klaase, Joost M. ;

van den Engh, Frank M. ;

Steenbergen, Wiendelt ;

van Leeuwen, Ton G. .

OPTICS EXPRESS, 2007, 15 (19) :12277-12285

[10] Vascular targeted nanoparticles for imaging and treatment of brain tumors [J].

Reddy, G. Ramachandra ;

Bhojani, Mahaveer S. ;

McConville, Patrick ;

Moody, Jonathan ;

Moffat, Bradford A. ;

Hall, Daniel E. ;

Kim, Gwangseong ;

Koo, Yong-Eun L. ;

Woolliscroft, Michael J. ;

Sugai, James V. ;

Johnson, Timothy D. ;

Philbert, Martin A. ;

Kopelman, Raoul ;

Rehemtulla, Alnawaz ;

Ross, Brian D. .

CLINICAL CANCER RESEARCH, 2006, 12 (22) :6677-6686

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