Elemental fluorine .5. Reactions of 1,3-dithiolanes and thioglycosides with fluorine-iodine mixtures

被引：23

作者：

Chambers, RD ^{[1
]}

Sandford, G ^{[1
]}

Sparrowhawk, ME ^{[1
]}

Atherton, MJ ^{[1
]}

机构：

[1] BNFL FLUOROCHEM LTD,PRESTON PR4 0XJ,LANCS,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1996年 / 16期

关键词：

D O I：

10.1039/p19960001941

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1,3-Dithiolanes, prepared from diaryl ketones, react with elemental fluorine-iodine mixtures to give the corresponding difluoromethylene derivatives. Under the same conditions, thioglycosides give glycosyl fluorides in good yields. Reaction of 1,3-dithiolanes with fluorine in aqueous acetonitrile provides a remarkably mild method for efficient deprotection to the parent ketone.

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页码：1941 / 1944

页数：4

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