The surface-tension-driven flow of blood from a droplet into a capillary tube

被引:36
作者
Huang, W [1 ]
Bhullar, RS
Fung, YC
机构
[1] Univ Calif San Diego, Dept Bioengn, La Jolla, CA 92093 USA
[2] Roche Diagnost Corp, Indianapolis, IN 46206 USA
来源
JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME | 2001年 / 123卷 / 05期
关键词
Capillary tubes - Flow of fluids - Navier Stokes equations - Shear stress - Surface tension - Tissue - Viscosity;
D O I
10.1115/1.1389096
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
In tissue, medical, or dental engineering, If-hen blood comes into contact with a new artificial material, the flow may, be influenced by surface tension between the blood and the surface of the material. The effect of surface tension on the flow of blood is significant, especially in microscale. The leading edge of the flowing blood is the triple point where the blood, the material surface, and a stationary gas or fluid meet. The movement of the triple point, i.e., the advancing front of the flow, is driven by v surface tension, resisted by viscous shear stress, and balanced by the inertial force (-mass X acceleration). In this article, the dynamics is illustrated in detail in the case of blood flowing into a capillary tube by contact. The capillary, tube draws the blood into it. It is shown theoretically that initially the flow of blood in the capillary has a large acceleration, followed by a relatively large deceleration over the next short period of time, then the acceleration becomes small and oscillatory. The velocity history appears impulsive at first, then slows down. The history of the length of blood column appears smooth after integration. Existing solutions of the Navier-Stokes equation permit the analysis of simpler cases. Further fluid mechanics development is needed to meet the practical needs of bioengineering. The importance of experimental study of surface tension and contact angle over a biological surface or a man-made material as a future direction of research is pointed out.
引用
收藏
页码:446 / 454
页数:9
相关论文
共 14 条
[1]  
Fung Y.-C., 1993, Biomechanics: Mechanical Properties of Living Tissues, P66, DOI [10.1007/978-1-4757-2257-4_3, DOI 10.1007/978-1-4757-2257-4_3]
[2]   DOES SURFACE-TENSION MAKE LUNG INHERENTLY UNSTABLE [J].
FUNG, YC .
CIRCULATION RESEARCH, 1975, 37 (04) :497-502
[3]  
FUNG YC, 1997, BIOMECHANICS CIRCULA, P291
[4]  
FUNG YC, 1990, ENG SCI FLUID DYNAMI, P135
[5]   ON LOW-REYNOLDS-NUMBER ENTRY FLOW INTO A CIRCULAR CYLINDRICAL TUBE [J].
LEW, HS ;
FUNG, YC .
JOURNAL OF BIOMECHANICS, 1969, 2 (01) :105-&
[6]   ENTRY FLOW INTO BLOOD VESSELS AT ARBITRARY REYNOLDS NUMBER [J].
LEW, HS ;
FUNG, YC .
JOURNAL OF BIOMECHANICS, 1970, 3 (01) :23-+
[7]  
Purday H.F.P., 1949, INTRO MECH VISCOUS F
[8]  
THURSTON G B, 1973, Biorheology, V10, P375
[9]   VISCOSITY AND VISCOELASTICITY OF BLOOD IN SMALL DIAMETER TUBES [J].
THURSTON, GB .
MICROVASCULAR RESEARCH, 1976, 11 (02) :133-146
[10]  
Tong P., 1965, FLUID MECH HEAT TRAN, DOI 633580