Atropisomers and near-atropisomers: achieving stereoselectivity by exploiting the conformational preferences of aromatic amides

被引：102

作者：

Clayden, J ^{[1
]}

机构：

[1] Univ Manchester, Dept Chem, Manchester M13 9PL, Lancs, England

来源：

CHEMICAL COMMUNICATIONS | 2004年 / 02期

关键词：

D O I：

10.1039/b307976g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The conformational preferences of aromatic amides are remarkably easy to control with a high degree of selectivity. This article reviews the consequences of this unusual form of stereocontrol, which enables for example the asymmetric synthesis of atropisomers and the ability to achieve remote stereocontrol by conformational relay.

引用

页码：127 / 135

页数：9

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