A water-soluble m-phenylene ethynylene foldamer

被引：99

作者：

Stone, MT ^{[1
]}

Moore, JS ^{[1
]}

机构：

[1] Univ Illinois, Dept Chem & Mat Sci & Engn, Urbana, IL 61801 USA

来源：

ORGANIC LETTERS | 2004年 / 6卷 / 04期

关键词：

D O I：

10.1021/ol036238k

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A water-soluble m-phenylene ethynylene (mPE) foldamer was realized by appending hexaethylene glycol side chains to the backbone repeat unit. UV spectra of the oligomer in aqueous solutions were consistent with a helical conformation. The association constant of the oligomer with (-)-alpha-pinene increased dramatically with increasing water composition, peaking at 90% water by volume in acetonitrile. The rate of the host/guest system's approach to equilibrium was found to decrease considerably with increasing water content.

引用

页码：469 / 472

页数：4

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