8-Allyldihydroberberine as an alternative precursor for the synthesis of 13-substituted berberine derivatives

被引:14
作者
Bremner, JB [1 ]
Samosorn, S
机构
[1] Univ Wollongong, Inst Biomol Sci, Wollongong, NSW 2522, Australia
[2] Univ Wollongong, Dept Chem, Wollongong, NSW 2522, Australia
关键词
D O I
10.1071/CH03054
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
An alternative route to 13-substituted derivatives of the biologically active alkaloid berberine has been developed based on the key synthetic precursor, 8-allyldihydroberberine.
引用
收藏
页码:871 / 873
页数:3
相关论文
共 10 条
  • [1] Retro-ene type fragmentation of allylic dithiolcarbonates
    Eto, M
    Nishimoto, M
    Kubota, S
    Matsuoka, T
    Harano, K
    [J]. TETRAHEDRON LETTERS, 1996, 37 (14) : 2445 - 2448
  • [2] HANAOKA M, 1984, CHEM PHARM BULL, V32, P2230
  • [3] Antibacterial activity and structure-activity relationships of berberine analogs
    Iwasa, K
    Kamigauchi, M
    Ueki, M
    Taniguchi, M
    [J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 1996, 31 (06) : 469 - 478
  • [4] Structure-activity relationships of quaternary protoberberine alkaloids having an antimalarial activity
    Iwasa, K
    Nishiyama, Y
    Ichimaru, M
    Moriyasu, M
    Kim, HS
    Wataya, Y
    Yamori, T
    Takashi, T
    Lee, DU
    [J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 1999, 34 (12) : 1077 - 1083
  • [5] Kim J.H., 2000, U.S. Patent, Patent No. [6,030,978, 6030978]
  • [6] Kim JH, 2001, US Patent, Patent No. [6,239,139B1, 6239139]
  • [7] ORGANIC AND BIOLOGICAL ASPECTS OF BERBERINE ALKALOIDS
    KONDO, Y
    [J]. HETEROCYCLES, 1976, 4 (01) : 197 - 219
  • [8] NARUTO S, 1975, CHEM PHARM BULL, V23, P1271
  • [9] TANI C, 1954, J PHARM SOC JAPAN, V74, P317
  • [10] VERPOORTE R, 1998, ALKALOIDS BIOCH ECOL, P414