Modifications of Small RNAs and Their Associated Proteins

被引:145
作者
Kim, Young-Kook [1 ,2 ]
Heo, Inha [1 ,2 ]
Kim, V. Narry [1 ,2 ]
机构
[1] Seoul Natl Univ, Sch Biol Sci, Seoul 151742, South Korea
[2] Seoul Natl Univ, Ctr Natl Creat Res, Seoul 151742, South Korea
基金
新加坡国家研究基金会;
关键词
PIWI-INTERACTING RNAS; EMBRYONIC STEM-CELLS; CAENORHABDITIS-ELEGANS; MICRORNA BIOGENESIS; 3' ADENYLATION; URIDYLATION; MIRNAS; SIRNAS; LIN28; PHOSPHORYLATION;
D O I
10.1016/j.cell.2010.11.018
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Small regulatory RNAs and their associated proteins are subject to diverse modifications that can impinge on their abundance and function. Some of the modifications are under the influence of cellular signaling, thus contributing to the dynamic regulation of RNA silencing.
引用
收藏
页码:703 / 709
页数:7
相关论文
共 54 条
  • [1] Target RNA-Directed Trimming and Tailing of Small Silencing RNAs
    Ameres, Stefan L.
    Horwich, Michael D.
    Hung, Jui-Hung
    Xu, Jia
    Ghildiyal, Megha
    Weng, Zhiping
    Zamore, Phillip D.
    [J]. SCIENCE, 2010, 328 (5985) : 1534 - 1539
  • [2] Differential regulation of microRNA stability
    Bail, Sophie
    Swerdel, Mavis
    Liu, Hudan
    Jiao, Xinfu
    Goff, Loyal A.
    Hart, Ronald P.
    Kiledjian, Megerditch
    [J]. RNA, 2010, 16 (05) : 1032 - 1039
  • [3] MicroRNAs: Target Recognition and Regulatory Functions
    Bartel, David P.
    [J]. CELL, 2009, 136 (02) : 215 - 233
  • [4] A comprehensive survey of 3′ animal miRNA modification events and a possible role for 3′ adenylation in modulating miRNA targeting effectiveness
    Burroughs, A. Maxwell
    Ando, Yoshinari
    de Hoon, Michiel J. L.
    Tomaru, Yasuhiro
    Nishibu, Takahiro
    Ukekawa, Ryo
    Funakoshi, Taku
    Kurokawa, Tsutomu
    Suzuki, Harukazu
    Hayashizaki, Yoshihide
    Daub, Carsten O.
    [J]. GENOME RESEARCH, 2010, 20 (10) : 1398 - 1410
  • [5] Down-Regulation of a Host MicroRNA by a Herpesvirus saimiri Noncoding RNA
    Cazalla, Demian
    Yario, Therese
    Steitz, Joan
    [J]. SCIENCE, 2010, 328 (5985) : 1563 - 1566
  • [6] Active turnover modulates mature microRNA activity in Caenorhabditis elegans
    Chatterjee, Saibal
    Grosshans, Helge
    [J]. NATURE, 2009, 461 (7263) : 546 - U120
  • [7] TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing
    Chendrimada, TP
    Gregory, RI
    Kumaraswamy, E
    Norman, J
    Cooch, N
    Nishikura, K
    Shiekhattar, R
    [J]. NATURE, 2005, 436 (7051) : 740 - 744
  • [8] Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
    Chiang, H. Rosaria
    Schoenfeld, Lori W.
    Ruby, J. Graham
    Auyeung, Vincent C.
    Spies, Noah
    Baek, Daehyun
    Johnston, Wendy K.
    Russ, Carsten
    Luo, Shujun
    Babiarz, Joshua E.
    Blelloch, Robert
    Schroth, Gary P.
    Nusbaum, Chad
    Bartel, David P.
    [J]. GENES & DEVELOPMENT, 2010, 24 (10) : 992 - 1009
  • [9] Human polynucleotide phosphorylase selectively and preferentially degrades microRNA-221 in human melanoma cells
    Das, Swadesh K.
    Sokhi, Upneet K.
    Bhutia, Sujit K.
    Azab, Belal
    Su, Zhao-zhong
    Sarkar, Devanand
    Fisher, Paul B.
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (26) : 11948 - 11953
  • [10] Arabidopsis FIERY1, XRN2, and XRN3 are endogenous RNA silencing suppressors
    Gy, Isabelle
    Gasciolli, Virginie
    Lauressergues, Dominique
    Morel, Jean-Benoit
    Gombert, Julie
    Proux, Florence
    Proux, Caroline
    Vaucheret, Herve
    Mallory, Allison C.
    [J]. PLANT CELL, 2007, 19 (11) : 3451 - 3461