Successful management of adult respiratory distress syndrome (ARDS) after high-dose chemotherapy and peripheral blood progenitor cell rescue by non-invasive ventilatory support

被引：19

作者：

Rabitsch, W

Staudinger, T

Brugger, SA

Reiter, E

Keil, F

Herold, C

Lechner, K

Greinix, HT

Kalhs, P

机构：

[1] Univ Vienna, Dept Internal Med 1, Bone Marrow Transplantat Unit, A-1090 Vienna, Austria

[2] Univ Vienna, Dept Internal Med 1, Intens Care Unit, A-1090 Vienna, Austria

[3] Univ Vienna, Dept Radiol, A-1090 Vienna, Austria

[4] Univ Vienna, Dept Internal Med 1, Hematol Unit, A-1090 Vienna, Austria

来源：

BONE MARROW TRANSPLANTATION | 1998年 / 21卷 / 10期

关键词：

high-dose chemotherapy and peripheral blood progenitor cell rescue non-invasive ventilatory support; non-invasive ventilation; CPAP; ARDS;

D O I：

10.1038/sj.bmt.1701215

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

A 34-year-old man suffering from Hodgkin's disease underwent high-dose chemotherapy (CBV) followed by transplantation of autologous peripheral blood stem cells. On day +6 after peripheral blood stem cell transplant (PBSCT) bacterial pneumonia developed. Along with rapid engraftment during stimulation with G-CSF adult respiratory distress syndrome (ARDS) developed within 4 days, High-flow CPAP (continuous positive airway pressure) ventilation via a sealed face-mask was initiated. The patient tolerated the sealed face-mask very well, and CPAP was continuously administered for 4 days, thus avoiding intubation, High-flow CPAP may offer a therapeutic alternative in selected patients with respiratory compromise after PBSCT.

引用

页码：1067 / 1069

页数：3

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