Exotic biomodification of fatty acids

被引:27
作者
Buist, Peter H. [1 ]
机构
[1] Carleton Univ, Dept Chem, Ottawa, ON K1S 5B6, Canada
关键词
D O I
10.1039/b508584p
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Many biotransformations of mid- to long chain fatty acyl derivatives are intrinsically interesting because of their high selectivity and novel mechanisms. These include one carbon transfer, hydration, isomerization, hydrogenation, ladderane and hydrocarbon formation, thiolation and various oxidative transformations such as epoxidation, hydroxylation and desaturation. In addition, hydroperoxidation of polyunsaturated fatty acids leads to a diverse array of bioactive compounds. The bioorganic aspects of selected reactions will be highlighted in this review; 210 references are cited.
引用
收藏
页码:1110 / 1127
页数:18
相关论文
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