ISG20, an actor of the innate immune response

被引：63

作者：

Degols, Genevieve ^{[1
]}

Eldin, Patrick ^{[1
]}

Mechti, Nadir ^{[1
]}

机构：

[1] CNRS, UMR160, EFS, F-34094 Montpellier 5, France

来源：

BIOCHIMIE | 2007年 / 89卷 / 6-7期

关键词：

interferon; exonuclease; ISG20; innate immune response;

D O I：

10.1016/j.biochi.2007.03.006

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

The interferon (IFN) system is a major effector of the innate immunity that allows time for the subsequent establishment of an adaptive immune response against wide-range pathogens. The effectiveness of IFN to control initial infection requires the cooperation between several pathways induced in the target cells. Recent studies that highlight the implication of the 3 '-5 ' exonuclease ISG20 (IFN Stimulated Gene product of 20 kDa) in the host's defenses against pathogens are summarised in this review. (C) 2007 Elsevier Masson SAS. All rights reserved.

引用

收藏

页码：831 / 835

页数：5

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