Drosophila melanogaster antimicrobial defense

被引：96

作者：

Hetru, C ^{[1
]}

Troxler, L ^{[1
]}

Hoffmann, JA ^{[1
]}

机构：

[1] CNRS, Inst Biol Mol & Cellulaire, UPR 9022, F-67084 Strasbourg, France

来源：

JOURNAL OF INFECTIOUS DISEASES | 2003年 / 187卷

关键词：

D O I：

10.1086/374758

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The Drosophila melanogaster host defense is complex but remarkably efficient. It is a multifaceted response to a variety of fungal, bacterial, and parasitic invaders. Current knowledge is discussed on recognition of infectious microorganisms and on the activation of intracellular signaling cascades that concur with the expression of numerous immune-responsive genes, among which, to date, the most prominent appear to encode potent antimicrobial peptides.

引用

页码：S327 / S334

页数：8

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