Particle design using supercritical fluids

New supercritical fluid based techniques for particle design are reviewed in this paper. Particular attention will be given to a new and promising technique that uses supercritical fluids to assist atomization processes. Using this new and versatile process, several water soluble compounds that cannot be treated by traditional supercritical fluid based techniques can be successfully micronized. Lipophilic compounds can also be successfully processed.