Affinity capillary electrophoresis in a poly(dimethylsiloxane)-glass hybrid microchip

被引：12

作者：

Ito, T ^{[1
]}

Inoue, A ^{[1
]}

Sato, K ^{[1
]}

Hosokawa, K ^{[1
]}

Maeda, M ^{[1
]}

机构：

[1] RIKEN, Inst Phys & Chem Res, Bioengn Lab, Wako, Saitama 3510198, Japan

来源：

CHEMISTRY LETTERS | 2003年 / 32卷 / 08期

关键词：

D O I：

10.1246/cl.2003.688

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Affinity capillary electrophoresis of DNA was conducted in a poly(dimethylsiloxane)-glass hybrid microchip with a 100 gm (width) x 130mum (height) microchannel containing poly(N,N-dimethylacrylamide)-DNA conjugate. By this method, sample 12-mer oligonucleotide composed of c-K-ras codon 10-13 was separated from its single-base substituted mutant within 2 min.

引用

页码：688 / 689

页数：2

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