AFM-tip-integrated amperometric microbiosensors: High-resolution imaging of membrane transport

被引：53

作者：

Kueng, A

Kranz, C ^{[1
]}

Lugstein, A

Bertagnolli, E

Mizaikoff, B

机构：

[1] Georgia Inst Technol, Sch Chem & Biochem, Atlanta, GA 30332 USA

[2] Vienna Univ Technol, Solid State Elect Inst, A-1040 Vienna, Austria

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 22期

关键词：

biosensors; glucose; membranes; scanning probe microscopy;

D O I：

10.1002/anie.200461556

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) A probing combination: Integration of amperometric microbiosensors into combined tips for AFM-scanning electrochemical microscopy allows specific detection of molecular species independent of the AFM measurement, but correlated in space and time with the surface morphology. The applicability of this multidimensional approach is demonstrated by imaging glucose transport across porous membranes at the nanoscale (see picture). © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：3419 / 3422

页数：4

共 24 条

[1]

Bard A. J., 1980, ELECTROCHEMICAL METH

[2] CHEMICAL IMAGING OF SURFACES WITH THE SCANNING ELECTROCHEMICAL MICROSCOPE [J].