α-chlorination of ketones using p-toluenesulfonyl chloride

被引：58

作者：

Brummond, KM ^{[1
]}

Gesenberg, KD ^{[1
]}

机构：

[1] W Virginia Univ, Dept Chem, Morgantown, WV 26506 USA

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 12期

关键词：

D O I：

10.1016/S0040-4039(99)00213-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of a variety of ketones with lithium diisopropylamide followed by p-toluenesulfonyl chloride gives alpha-chloroketones in goad yields. In addition, a polymer bound tosyl chloride reagent has also been shown to effect this transformation. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：2231 / 2234

页数：4

共 13 条

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