Methylation of zinc bound thiolates; a model for cobalamine independent methionine synthase

被引:57
作者
Brand, U [1 ]
Rombach, M [1 ]
Vehrenkamp, H [1 ]
机构
[1] Univ Freiburg, Inst Anorgan & Analyt Chem, D-79104 Freiburg, Germany
关键词
D O I
10.1039/a807326k
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Pyrazolylborate-zinc-thiolate complexes react under mild conditions with methyl iodide, dimethylsulfate and trimethylsulfonium iodide, liberating the corresponding methyl thioethers; the driving force for these reactions lies in the high nucleophilicity of the zinc-bound thiolates and the low donor quality of thioethers toward zinc.
引用
收藏
页码:2717 / 2718
页数:2
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