The two human organic cation transporter genes SLC22A1 and SLC22A2 are located on chromosome 6q26

被引：49

作者：

Koehler, MR

Wissinger, B

Gorboulev, V

Koepsell, H

Schmid, M

机构：

[1] Univ Wurzburg, Inst Anat, Dept Anat, D-97070 Wurzburg, Germany

[2] Univ Wurzburg, Biozentrum, Dept Human Genet, Wurzburg, Germany

[3] Univ Tubingen, Hosp Eye, Genet Mol Lab, Tubingen, Germany

来源：

CYTOGENETICS AND CELL GENETICS | 1997年 / 79卷 / 3-4期

关键词：

D O I：

10.1159/000134720

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Polyspecific transporters for organic cations (OCT) belong to a new protein family which also include organic anion transporters. The first human transporters from this family (OCT1, OCT2) have been recently cloned. They translocate small cations like tetraethylammonium, choline and monoamine neurotransmitters and are involved in hepatic and renal cation excretion, respectively. We have localized the OCT1 and OCT2 genes (SLC22A1, SLC22A2) on chromosome 6q26.

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页码：198 / 200

页数：3

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