Reactions of α-monochloro- and α,α-dichloro-β-oxoaldehyde acetals with bases

被引：2

作者：

Guseinov, FI ^{[1
]}

机构：

[1] Kazan State Technol Univ, Kazan 420015, Russia

来源：

RUSSIAN CHEMICAL BULLETIN | 1998年 / 47卷 / 04期

关键词：

alpha; alpha-dichloro-beta-oxoaldehyde acetals; base; carbanion; benzaldehyde; intramolecular nucleophilic reaction;

D O I：

10.1007/BF02495974

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

alpha,alpha-Dichloro-beta-oxoaldehyde diethyl acetals decompose under the action of bases (NaOH, MeONa) with cleavage of the carbon-carbon bond and formation of carboxylic acids or their esters and the dichloroacetaldehyde diethyl acetal carbanion. The latter reacts in situ with benzaldehyde to form stable alpha-chloro-alpha,beta-epoxyacetal. alpha-Chloro-alpha-formly-gamma-butyrolactone diethyl acetal is transformed into alpha-chloro-alpha-diethoxymethyl-gamma-hydroxybutyric acid under the action of an alkali.

引用

页码：663 / 665

页数：3