Our Unindicted Coconspirators: Human Metabolism from a Microbial Perspective

被引:60
作者
Goodman, Andrew L. [1 ]
Gordon, Jeffrey I. [1 ]
机构
[1] Washington Univ, Sch Med, Ctr Genome Sci & Syst Biol, St Louis, MO 63108 USA
关键词
GUT MICROBIOTA; RECEPTOR;
D O I
10.1016/j.cmet.2010.07.001
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The human gut is populated by a microbiota composed of tens of trillions of organisms and millions of genes that together form a metabolic "organ." Intra- and interpersonal differences in the structure and functions of this organ suggest that it could contribute to our normal metabolic variations and also to metabolic disorders. This Commentary discusses experimental approaches for connecting microbial and host metabolism in the context of health and disease.
引用
收藏
页码:111 / 116
页数:6
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