Kinetic resolution of cyclic acetals derived from 1,3-alkanediols via oxazaborolidine-mediated enantioselective ring-cleavage reaction

被引：12

作者：

Harada, T ^{[1
]}

Egusa, T ^{[1
]}

Kinugasa, M ^{[1
]}

Oku, A ^{[1
]}

机构：

[1] Kyoto Inst Technol, Dept Chem, Sakyo Ku, Kyoto 606, Japan

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 31期

关键词：

acetals; asymmetric induction; cleavage reactions; resolution;

D O I：

10.1016/S0040-4039(98)01091-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Racemic acetals derived from 1,3-alkanediols undergo kinetic resolution with a selectivity factor s = 5.2-14 in ring-cleavage reaction with methallyldimethylphenylsilane mediated by a N-mesylphenylalanine derived oxazaborolidine. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：5531 / 5534

页数：4

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