5-HT1-like receptors:: a time to bid goodbye

被引：76

作者：

Saxena, PR

De Vries, P

Villalón, CM

机构：

[1] Erasmus Univ, Fac Med & Hlth Sci, Dept Pharmacol, NL-3000 DR Rotterdam, Netherlands

[2] CINVESTAV, IPN, Dept Farmacol, Secc Terapeut Expt, Mexico City 14000, DF, Mexico

来源：

TRENDS IN PHARMACOLOGICAL SCIENCES | 1998年 / 19卷 / 08期

关键词：

D O I：

10.1016/S0165-6147(98)01228-0

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

It is exactly half a century ago that 5-hydroxytryptamine was discovered and over four decades ago two types of 5-HT receptors were described. In this article, Pramod Saxena, Peter De Vries and Caries Villalon trace the development of the modern classification and nomenclature of 5-HT receptors, which now include more than a dozen subtypes. In doing so, they advocate that the so-called '5-HT1-like' receptors, having been shown to be a heterogeneous population of 5-HT1B, 5-HT1D and 5-HT7 receptors, are now redundant.

引用

收藏

页码：311 / 316

页数：6

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