Intravesical instillation of cidofovir in the treatment of hemorrhagic cystitis caused by adenovirus type II in a bone marrow transplant recipient

被引：50

作者：

Fanourgiakis, P

Georgala, A

Vekemans, M

Triffet, A

De Bruyn, JM

Duchateau, V

Martiat, P

De Clercq, E

Snoeck, R

Wollants, E

Rector, A

Van Ranst, M

Aoun, M

机构：

[1] Inst Jules Bordet, Dept Internal Med, B-1000 Brussels, Belgium

[2] Inst Jules Bordet, Infect Dis Dept, B-1000 Brussels, Belgium

[3] Katholieke Univ Leuven, Rega Inst Med Res, Louvain, Belgium

来源：

CLINICAL INFECTIOUS DISEASES | 2005年 / 40卷 / 01期

关键词：

D O I：

10.1086/426594

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Hemorrhagic cystitis that occurs late after bone marrow transplantation ( BMT) in BMT recipients is often associated with adenovirus or polyomavirus BK infections. Intravesical instillation of cidofovir in a BMT recipient with intractable hemorrhagic cystitis resulted in clinical improvement. Local cidofovir therapy for viral hemorrhagic cystitis could be an alternative to intravenous administration of cidofovir.

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页码：199 / 201

页数：3

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