Mode of action of lufenuron on larval cat fleas (Siphonaptera: Pulicidae)

被引:35
作者
Dean, SR [1 ]
Meola, RW
Meola, SM
Sittertz-Bhatkar, H
Schenker, R
机构
[1] Texas A&M Univ, Dept Entomol, College Stn, TX 77843 USA
[2] ARS, Food Anim Protect Lab, USDA, College Stn, TX 77845 USA
[3] Texas A&M Univ, Ctr Electron Microscopy, College Stn, TX 77843 USA
[4] Novartis Prod AG, Anim Hlth Sector, CH-4002 Basel, Switzerland
关键词
Ctenocephalides felis; lufenuron; chitin synthesis inhibitor; cuticle;
D O I
10.1093/jmedent/35.5.720
中图分类号
Q96 [昆虫学];
学科分类号
摘要
Adult cat fleas, Ctenocephalides felis (Bouche), were fed suboptimal in vitro concentrations of lufenuron in blood to allow hatching of flea larvae for cytological study. At concentrations of 0.125, 0.25, and 0.5 ppm, larval hatch was 64, 15, and 4%, respectively. Larvae hatching from eggs laid by adults fed lufenuron at concentrations of 0.025, 0.08, or 0.125 ppm did not differ significantly from the control. However, many larvae from the 0.08-ppm group and higher concentrations died during the 1st instar. Examination of these larvae revealed that they were dying from desiccation caused by bleeding from microscopic lesions in the cuticle or the inability to complete the molt to the nest instar. Electron micrographs showed that lufenuron often disrupted formation of the endocuticle resulting in the deposition of ari amorphous mass of randomly oriented chitin microfibrils. Other larvae formed normal endocuticle but were unable to digest the old endocuticle or produce new procuticle after apolysis. Failure of larvae to digest old cuticle or form new cuticle was caused by degeneration of the epidermal cells needed for the synthesis of molting fluid and chitin.
引用
收藏
页码:720 / 724
页数:5
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