A new approach to (9Z)-Dodec-9-en-12-olide (Yuzu lactone) via phase transfer catalysis cyclization

被引：14

作者：

Rodefeld, L ^{[1
]}

Tochtermann, W ^{[1
]}

机构：

[1] Univ Kiel, Inst Organ Chem, D-24098 Kiel, Germany

来源：

TETRAHEDRON | 1998年 / 54卷 / 22期

关键词：

cyclization; flavours and fragrances; macrolides; natural products; phase transfer; Wittig reactions;

D O I：

10.1016/S0040-4020(98)00268-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

(9Z)-Dodec-9-en-12-olide (1), also known as "Yuzu lactone", a volatile ingredient of Yuzu fruit was prepared in a three step synthesis via Z-selective Wittig olefination, a deprotection and activation protocol and subsequent cyclization by solid-liquid phase transfer catalysis under avoidance of high dilution conditions. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：5893 / 5898

页数：6

共 15 条

[1] REACTIONS OF ALKYLIDENETRIPHENYLPHOSPHORANES .33. PREPARATIONS OF LITHIUM SALTFREE YLID SOLUTIONS WITH SODIUM BIS(TRIMETHYLSILYL)AMIDE AS BASE [J].