EMDataBank.org: unified data resource for CryoEM

被引:205
作者
Lawson, Catherine L. [1 ]
Baker, Matthew L. [2 ]
Best, Christoph [3 ]
Bi, Chunxiao [1 ]
Dougherty, Matthew [2 ]
Feng, Powei [4 ]
van Ginkel, Glen [3 ]
Devkota, Batsal [1 ]
Lagerstedt, Ingvar [3 ]
Ludtke, Steven J. [2 ]
Newman, Richard H. [3 ]
Oldfield, Tom J. [3 ]
Rees, Ian [2 ]
Sahni, Gaurav [3 ]
Sala, Raul [1 ]
Velankar, Sameer [3 ]
Warren, Joe [4 ]
Westbrook, John D. [1 ]
Henrick, Kim [3 ]
Kleywegt, Gerard J. [3 ]
Berman, Helen M. [1 ]
Chiu, Wah [2 ]
机构
[1] Rutgers State Univ, Dept Chem & Chem Biol, Piscataway, NJ 08854 USA
[2] Baylor Coll Med, Natl Ctr Macromol Imaging, Dept Biochem & Mol Biol, Houston, TX 77030 USA
[3] EMBL EBI, Prot Data Bank Europe, Cambridge CB10 1SD, England
[4] Rice Univ, Dept Comp Sci, Houston, TX 77251 USA
基金
美国国家卫生研究院; 英国生物技术与生命科学研究理事会;
关键词
X-RAY CRYSTALLOGRAPHY; ELECTRON-MICROSCOPY; DENGUE VIRUS; CRYOELECTRON MICROSCOPY; 3-DIMENSIONAL STRUCTURE; ENVELOPE PROTEIN; STRUCTURAL BASIS; BACKBONE TRACE; DENSITY MAPS; CRYOMICROSCOPY;
D O I
10.1093/nar/gkq880
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Cryo-electron microscopy reconstruction methods are uniquely able to reveal structures of many important macromolecules and macromolecular complexes. EMDataBank.org, a joint effort of the Protein Data Bank in Europe (PDBe), the Research Collaboratory for Structural Bioinformatics (RCSB) and the National Center for Macromolecular Imaging (NCMI), is a global 'one-stop shop' resource for deposition and retrieval of cryoEM maps, models and associated metadata. The resource unifies public access to the two major archives containing EM-based structural data: EM Data Bank (EMDB) and Protein Data Bank (PDB), and facilitates use of EM structural data of macromolecules and macromolecular complexes by the wider scientific community.
引用
收藏
页码:D456 / D464
页数:9
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