Triterpene glycosides from the roots of Astragalus flavescens

被引：33

作者：

Avunduk, Sibel ^{[2
,3
]}

Mitaine-Offer, Anne-Claire ^{[1
]}

Alankus-Caliskan, Oezgen ^{[2
]}

Miyamoto, Tomofumi ^{[4
]}

Senol, Serdar Goekhan ^{[5
]}

Lacaille-Dubois, Marie-Aleth ^{[1
]}

机构：

[1] Univ Bourgogne, Fac Pharm, Lab Pharmacognosie, UMIB,UPRES EA 3660, F-21079 Dijon, France

[2] Ege Univ, Fac Sci, Dept Chem, TR-35100 Izmir, Turkey

[3] Mugla Univ, Vocat Sch Hlth Care, Med Lab Programme, TR-48187 Marmaris, Mugla, Turkey

[4] Kyushu Univ, Grad Sch Environm Sci, Fukuoka 8128582, Japan

[5] Ege Univ, Fac Sci, Dept Bot, TR-35100 Izmir, Turkey

来源：

JOURNAL OF NATURAL PRODUCTS | 2008年 / 71卷 / 01期

关键词：

D O I：

10.1021/np0703500

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Six new triterpene saponins, 3-O-alpha-L-rhamnopyranosyl-(1 -> 2)-beta-D-Xylopyranosyl-(1 -> 2)-beta-D-glucuronopyranosyl-21-epi-kudzusapogenol A (1), 3-O-alpha-L-rhamnopyranosyl-(1 -> 2)-beta-D-glucopyranosyl-(1 -> 2)-beta-D-glucuronopyranosyl-21-epi-kudzusapogenol A (2), 3-O-alpha-L-rhamnopyranosyl-(1 -> 2)-beta-D-Xylopyranosyl-(1 -> 2)-beta-D-glueuronopyranosyl-22-beta-D-glucopyranosyl-21-epi-kudzusapogenoI A (3), 3-O-alpha-L-rhamnopyranosyl-(1 -> 2)-beta-D-glueopyranosyl-(1 -> 2)-beta-D-glucuronopyranosy1-22-O-alpha-D-glucopyranosyl-21-epi-kudzusapogenol A (4), 3-O-alpha-L-rhamnopyranosyl-(1 -> 2)-beta-D-xylopyranosyl-(1 -> 2)-beta-D-glucuronopyranosyl-22-O-alpha-L-arabinopyranosyl-21-epi-kudzusapogenol A (5), and 3-O-alpha-L-rhamnopyranosyl-(1-2)-beta-D-glucopyranosyl-(1-2)-beta-D-glueuronopyranosyl-22-O-alpha-L-arabinopyranosyl-21-epi-kudzusapogenol A (6), were isolated from the roots of Astragalus flavescens, together with the known trajanoside B, azukisaponin V, and astragalosides IV, VII, and VIII. Their structures were established mainly by 2D NMR techniques and mass spectrometry.

引用

页码：141 / 145

页数：5

共 12 条

[1] Preventive effects of saponins from the Pueraria lobata root on in vitro immunological liver injury of rat primary hepatocyte cultures [J].

Arao, T ;

Udayama, M ;

Kinjo, J ;

Nohara, T .

PLANTA MEDICA, 1998, 64 (05) :413-416

[2] Secondary metabolites from the roots of Astragalus trojanus [J].

Bedir, E ;

Çalis, I ;

Aquino, R ;

Piacente, S ;

Pizza, C .

JOURNAL OF NATURAL PRODUCTS, 1999, 62 (04) :563-568

[3]

Davis P. H., 1970, FLORA TURKEY E AEGEA, V3, P49

[4] Anti-herpes virus type 1 activity of oleanane-type triterpenoids [J].

Ikeda, T ;

Yokomizo, K ;

Okawa, M ;

Tsuchihashi, R ;

Kinjo, J ;

Nohara, T ;

Uyeda, M .

BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2005, 28 (09) :1779-1781

[5]

KINJO J, 1985, CHEM PHARM BULL, V33, P1293

[6]

KITAGAWA I, 1983, CHEM PHARM BULL, V31, P716

[7]

KITAGAWA I, 1983, CHEM PHARM BULL, V31, P683

[8]

KONOSHIMA T, 1989, CHEM PHARM BULL, V37, P2731, DOI 10.1248/cpb.37.2731

[9] Triterpene saponins from the roots of Clematis chinensis [J].

Mimaki, Y ;

Yokosuka, A ;

Hamanaka, M ;

Sakuma, C ;

Yamori, T ;

Sashida, Y .

JOURNAL OF NATURAL PRODUCTS, 2004, 67 (09) :1511-1516

[10] A new oleanane glycoside from the roots of Astragalus caprinus [J].

Mitaine-Offer, Anne-Claire ;

Miyamoto, Tomofumi ;

Semmar, Nabil ;

Jay, Maurice ;

Lacaille-Dubois, Marie-Aleth .

MAGNETIC RESONANCE IN CHEMISTRY, 2006, 44 (07) :713-716

← 1 2 →