Rapid cycling in women and men with bipolar manic-depressive disorders

被引:101
作者
Tondo, L
Baldessarini, RJ
机构
[1] Harvard Univ, Sch Med, Dept Psychiat, Int Consortium Bipolar Disorder Res, Boston, MA 02115 USA
[2] Harvard Univ, Sch Med, Program Neurosci, Boston, MA 02115 USA
[3] Massachusetts Gen Hosp, Mailman Res Ctr, McLean Div, Boston, MA 02114 USA
[4] Stanley Fdn European Psychiat Res Ctr, Ctr Lucio Bini, Sardinia, Italy
关键词
D O I
10.1176/ajp.155.10.1434
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Objective: This study investigated risks for rapid cycling, as defined by DSM-IV, in women and men with bipolar disorders. Method: The results of 10 studies with a total of 2,057 bipolar patients were meta-analyzed by pooled contingency methods. Results: The proportions of women and men among rapid-cycling cases averaged 72% and 28%, respectively, but the risk of rapid cycling was inconsistently more frequent among women (29.6%) than among men (16.5%). The mean number of episodes per year was much higher in rapid-cycling patients before and during lithium treatment but was similar in rapid-cycling men and women. Conclusions: Rapid cycling was only moderately, and inconsistently, more common in bipolar women than men.
引用
收藏
页码:1434 / 1436
页数:3
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