Interrelationship between diabetes and homocysteine metabolism:: Hormonal regulation of cystathionine β-synthase

被引：25

作者：

Schalinske, KL ^{[1
]}

机构：

[1] Iowa State Univ, Dept Food Sci & Human Nutr, Ames, IA 50011 USA

来源：

NUTRITION REVIEWS | 2003年 / 61卷 / 04期

关键词：

homocysteine; diabetes; transsulfuration; insulin; cystathionine beta-synthase;

D O I：

10.1301/nr.2003.apr.136-138

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 [营养与食品卫生学];

摘要：

Plasma homocysteine levels are elevated during diabetes when there is atherosclerosis or insufficient renal function; however, diminished plasma homocysteine concentrations are observed in diabetes without complications. Recent studies have demonstrated that under diabetic conditions, the catabolism of homocysteine was enhanced by transcriptional regulation of hepatic cystathionine beta-synthase and these changes were prevented by treatment with insulin. (C) 2003 International Life Sciences Institute.

引用

页码：136 / 138

页数：3

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