THE EUGENE LANGUAGE FOR SYNTHETIC BIOLOGY

被引:9
作者
Bilitchenko, Lesia [1 ]
Liu, Adam [2 ]
Densmore, Douglas [3 ,4 ]
机构
[1] Calif State Polytech Univ Pomona, Dept Comp Sci, Pomona, CA 91768 USA
[2] Univ Calif Berkeley, Dept Elect Engn & Comp Sci, Berkeley, CA 94720 USA
[3] Boston Univ, Dept Biomed Engn, Boston, MA 02215 USA
[4] Boston Univ, Dept Elect & Comp Engn, Boston, MA 02215 USA
来源
SYNTHETIC BIOLOGY, PT B: COMPUTER AIDED DESIGN AND DNA ASSEMBLY | 2011年 / 498卷
关键词
D O I
10.1016/B978-0-12-385120-8.00007-3
中图分类号
Q5 [生物化学];
学科分类号
070307 [化学生物学];
摘要
Synthetic biological systems are currently created by an ad hoc, iterative process of design, simulation, and assembly. These systems would greatly benefit from the introduction of a more formalized and rigorous specification of the desired system components as well as constraints on their composition. In order to do so, the creation of robust and efficient design flows and tools is imperative. We present a human readable language (Eugene) which allows for both the specification of synthetic biological designs based on biological parts as well as providing a very expressive constraint system to drive the creation of composite devices from collection of parts. This chapter provides an overview of the language primitives as well as instructions on installation and use of Eugene v0.03b.
引用
收藏
页码:153 / 172
页数:20
相关论文
共 1 条
[1]
LESIA B, 2011, PLOS ONE