Casein kinase I: From obscurity to center stage

被引：71

作者：

Vielhaber, E ^{[1
]}

Virshup, DM ^{[1
]}

机构：

[1] Univ Utah, Huntsman Canc Inst, Ctr Children, Dept Pediat & Oncol Sci, Salt Lake City, UT 84112 USA

来源：

IUBMB LIFE | 2001年 / 51卷 / 02期

关键词：

casein kinase I; NFAT4; nuclear import; circadian rhythm; Wnt signaling; Alzheimer's disease;

D O I：

10.1080/15216540152122049

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The casein kinase I (CKI) family of protein kinases is a group of highly related, ubiquitously expressed serine/threonine kinases found in all eukaryotic organisms from protozoa to man. Recent advances in diverse fields, including developmental biology and chronobiology, have elucidated roles for CKI in regulating critical processes such as Wnt signaling, circadian rhythm, nuclear import, and Alzheimer's disease progression.

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收藏

页码：73 / 78

页数：6

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