Persistent pain in a community-based sample of children and adolescents: Sex differences in psychological constructs

S Fuss, MG Page, Joel Katz. Persistent pain in a community-based sample of children and adolescents: Sex differences in psychological constructs. Pain Res Manage 2011;16(5):303-309. BACKGROUND: Very few studies have investigated the psychological factors associated with the pain experiences of children and adolescents in community samples. OBJECTIVES: To examine the lifetime prevalence of, and psychological variables associated with, persistent pain in a community sample of children and adolescents, and to explore differences according to sex, age and pain history. METHODS: Participants completed the Childhood Anxiety Sensitivity Index (CASI), the Child Pain Anxiety Symptoms Scale (CPASS), the Multidimensional Anxiety Scale for Children-10 (MASC-10), the Pain Catastrophizing Scale for Children (PCS-C) and a pain history questionnaire that assessed chronicity and pain frequency. After research ethics board approval, informed consent/assent was obtained from 1022 individuals recruited to participate in a study conducted at the Ontario Science Centre (Toronto, Ontario). RESULTS: Of the 1006 participants (54% female, mean [+/- SD] age 11.6 +/- 2.7 years) who provided complete data, 27% reported having experienced pain that lasted for three months or longer. A 2x2x2 (pain history, age and sex) multivariate ANOVA was conducted, with the total scores on the CASI, the CPASS, the MASC-10 and the PCS-C as dependent variables. Girls with a history of persistent pain expressed higher levels of anxiety sensitivity (P<0.001) and pain catastrophizing (P<0.001) than both girls without a pain history and boys regardless of pain history. This same pattern of results was found for anxiety and pain anxiety in the older, but not the younger, age group. CONCLUSIONS: Boys and girls appear to differ in terms of how age and pain history relate to the expression of pain-related psychological variables. Given the prevalence of persistent pain found in the study, more research is needed regarding the developmental implications of persistent pain in childhood and adolescence.