Starvation, cessation of growth and bacterial aging

被引:51
作者
Nyström, T [1 ]
机构
[1] Univ Gothenburg, Dept Cell & Mol Biol Microbiol, S-41390 Gothenburg, Sweden
基金
瑞典研究理事会;
关键词
D O I
10.1016/S1369-5274(99)80037-X
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Several components of different Escherichia coli regulons are integrated to prevent premature oxidative deterioration of starving cells; The interconnected regulation of these regulons encompasses oxidation signalling, sigma factor competition, and possibly also the use of sigma factor inhibitors. Recent data demonstrate that stasis-induced oxidation targets both DNA and protein and that some enzymes are specifically susceptible to oxidative attack.
引用
收藏
页码:214 / 219
页数:6
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