Sensitivity of Influenza Rapid Diagnostic Tests to H5N1 and 2009 Pandemic H1N1 Viruses

被引：59

作者：

Sakai-Tagawa, Yuko ^{[1
]}

Ozawa, Makoto ^{[2
,8
]}

Tamura, Daisuke ^{[1
]}

Mai Thi Quynh Le ^{[6
]}

Nidom, Chairul A. ^{[7
]}

Sugaya, Norio ^{[3
]}

Kawaoka, Yoshihiro ^{[1
,2
,4
,5
,8
]}

机构：

[1] Univ Tokyo, Inst Med Sci, Div Virol, Dept Microbiol & Immunol,Minato Ku, Tokyo 1088639, Japan

[2] Univ Tokyo, Inst Med Sci, Int Res Ctr Infect Dis, Minato Ku, Tokyo 1088639, Japan

[3] Keiyu Hosp, Dept Pediat, Yokohama, Kanagawa 2200012, Japan

[4] Japan Sci & Technol Agcy, ERATO Infect Induced Host Responses Project, Kawaguchi, Saitama 3320012, Japan

[5] Kobe Univ, Div Zoonosis, Dept Microbiol & Infect Dis, Grad Sch Med, Kobe, Hyogo 6500017, Japan

[6] Natl Inst Hyg & Epidemiol, Hanoi, Vietnam

[7] Airlangga Univ, Fac Vet Med, Trop Dis Ctr, Surabaya, Indonesia

[8] Univ Wisconsin, Sch Vet Med, Dept Pathobiol Sci, Madison, WI 53706 USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2010年 / 48卷 / 08期

基金：

日本学术振兴会; 日本科学技术振兴机构;

关键词：

A VIRUS; INFECTION; PERFORMANCE; KITS;

D O I：

10.1128/JCM.00439-10

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Simple and rapid diagnosis of influenza is useful for making treatment decisions in the clinical setting. Although many influenza rapid diagnostic tests (IRDTs) are available for the detection of seasonal influenza virus infections, their sensitivity for other viruses, such as H5N1 viruses and the recently emerged swine origin pandemic (H1N1) 2009 virus, remains largely unknown. Here, we examined the sensitivity of 20 IRDTs to various influenza virus strains, including H5N1 and 2009 pandemic H1N1 viruses. Our results indicate that the detection sensitivity to swine origin H1N1 viruses varies widely among IRDTs, with some tests lacking sufficient sensitivity to detect the early stages of infection when the virus load is low.

引用

页码：2872 / 2877

页数：6

共 27 条

[1]

Bell D, 2006, EMERG INFECT DIS, V12, P81

[2]

Centers for Disease Control and Prevention (CDC), 2009, MMWR Morb Mortal Wkly Rep, V58, P1029

[3] Rapid clinical diagnosis in fatal swine influenza (H1N1) pneumonia in an adult with negative rapid influenza diagnostic tests (RIDTs): Diagnostic swine influenza triad [J].