Diabetes and Cancer: A Consensus Report

被引：576

作者：

Giovannucci, Edward ^{[1
,2
]}

Harlan, David M. ^{[3
,4
,5
]}

Archer, Michael C. ^{[6
,7
]}

Bergenstal, Richard M. ^{[8
]}

Gapstur, Susan M. ^{[9
]}

Habel, Laurel A. ^{[10
]}

Pollak, Michael ^{[11
]}

Regensteiner, Judith G. ^{[12
]}

Yee, Douglas ^{[13
]}

机构：

[1] Harvard Univ, Sch Publ Hlth, Dept Nutr, Boston, MA 02115 USA

[2] Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA

[3] Univ Massachusetts, Diabet Ctr Excellence, Mem Med Ctr, Worcester, MA 01605 USA

[4] Univ Massachusetts, Sch Med, Dept Med, Worcester, MA 01605 USA

[5] Univ Massachusetts, Sch Med, Dept Pediat, Worcester, MA 01605 USA

[6] Univ Toronto, Fac Med, Dept Nutr Sci, Toronto, ON, Canada

[7] Univ Toronto, Fac Med, Dept Med Biophys, Toronto, ON, Canada

[8] Int Diabet Ctr Pk Nicollet, Minneapolis, MN USA

[9] Amer Canc Soc, Epidemiol Res Program, Atlanta, GA 30329 USA

[10] Kaiser Permanente, Div Res, Oakland, CA USA

[11] McGill Univ, Dept Oncol, Montreal, PQ, Canada

[12] Univ Colorado, Sch Med, Aurora, CO USA

[13] Univ Minnesota, Mason Canc Ctr, Minneapolis, MN USA

来源：

CA-A CANCER JOURNAL FOR CLINICIANS | 2010年 / 60卷 / 04期

基金：

美国国家卫生研究院;

关键词：

ACTIVATED RECEPTOR-GAMMA; BODY-MASS INDEX; LIFE-STYLE INTERVENTION; BREAST-CANCER; INSULIN-RECEPTOR; PHYSICAL-ACTIVITY; GLYCEMIC INDEX; PPAR-GAMMA; IGF-I; RISK;

D O I：

10.3322/caac.20078

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Epidemiologic evidence suggests that cancer incidence is associated with diabetes as well as certain diabetes risk factors and treatments. This consensus statement of experts assembled jointly by the American Diabetes Association and the American Cancer Society reviews the state of science concerning 1) the association between diabetes and cancer incidence or prognosis; 2) risk factors common to both diabetes and cancer; 3) possible biologic links between diabetes and cancer risk; and 4) whether diabetes treatments influence the risk of cancer or cancer prognosis. In addition, key unanswered questions for future research are posed. CA Cancer J Clin 2010;60: 207-221. (C) 2010 by the American Diabetes Association and the American Cancer Society, Inc.

引用

页码：207 / 221

页数：15

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